Nanoscience and Nanotechnology

Nano Drug Delivery

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Recently, nanoparticles have aroused attention due to their potential application for effective drug delivery. Despite the many advantages of nanoparticles, there are also many challenges, including but not exclusively like biodistribution, Nanotoxicity and accumulation, and the clearance of nanoparticles by human body. Now a days Nanotechnology is used to cure the diseases like cancer and cardiovascular disease. Nanomaterials exhibit different physical and chemical properties or biological effects compared to larger-scale counterparts that can be beneficial for drug delivery systems. Some important advantages of nanoparticles is their high surface-area-to-volume ratio, geometric tunability, and chemical and their ability to interact with biomolecules to facilitate uptake across the cell membrane. The large surface area also has a large affinity for drugs and small molecules, like ligands or antibodies, for targeting and controlled release purposes. Nanoparticles refer to a large family of materials both inorganic and organic. Each material has uniquely tunable properties and thus can be selectively designed for specific applications. The National Institute of Biomedical Imaging and Bioengineering has issued the following prospects for future research in nanoparticle drug delivery systems like crossing the blood-brain barrier (BBB) in brain diseases and disorders, enhancing targeted intracellular delivery to ensure the treatments reach the correct structures inside cells, combining diagnosis and treatment. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency.